Probably my top picks from the E3 would be:
Splinter Cell: Blacklist (Loved Conviction)
Assassin's Creed 3 (the open-word god-like killer named Connor is pretty epic)
Watch Dogs (Very interesting concept)
ZombiU (Puts pretty much every RE and SH wannabe to shame)
PlanetSide 2 (The TotalBiscuit streams were pretty epic, a Free-to-play MMOFPS that looks more promising that 60 dollar shooters like CoD)
and Resident Evil 6. (Move and Shoot, CQC/Melee, and Real-time graphics that rival that of the CG movies)
EDIT: Oh, and Injustice looks like fun, if not very over-the-top...I do hope they show more since the graphics and gameplay have plenty of potential.